If you take baby steps on you tuneup and 2 degrees for every 50 nitrous hp you will be fine.
Aries told me that 75 hp shot nitrous is all that my pistons would take. Well, I'm at 175 hp now and no problems. Our tuneup is that good though. Every pass we read the plugs and every three passes we put a new set of plugs in it. NGK make a awsome nitrous plug that if the cylinder run to lean it will burn the grounding strap off and put that cylinder out. That will keep it from burning a hole in the piston.
My new King Sissell headed 292 motor will have JE nitrous pistons, GRP nitrous rods and 2 NOS fogger kits. I think we can make 900-1000 hp. This is what happen's to a bracket racer that start's hangging OUTLAW street car guy's.
Steven