i have a chevy 250. i cant believe that a 500 holley could feed enough fuel to the engine even on 10lbs of boost, unless the engine is really inefficient. the only reason i say that is becuase i ran a 600 holley 4 barrel on my old 250 that had some mods to it and it never ran rich. also, i did some calculations and the fuel requirement for 15lbs of boost would be upwards of 600cfm so i was thinking it would be safer to go a little bigger that way i wouldnt have to worry about starving my engine and detonation occuring.
please, all you knowledgeable people out there speak up on this.