That's a really good question. I guess draw through turbo setups wouldn't be any different that normal cause they're at atmospheric. But pressurized carbs I don't know. I'm not sure how the airflow would work. But I know this: you would need to be able to flow a lot of fuel. If the carb physically doesn't have big enough jets or gas passages to get enough fuel through you're in trouble. Which makes me think that a 300CFM carb might not be up to the job of supplying 600 CFM worth of fuel (at twice atmospheric pressure). I don't know.
