Chrysler was a big fan of crossover pipes on their large engines in the 60's and early 70's to reduce noise and also a crossover equalizes the pressure pulses which aids lower end torque somewhat. As far as inlines go none of the Big 3 ever bothered to build engines like we do with them so duals and crossovers have no history we can look back on. But across the big pond to our West, Honda used crossover pipes at one time or another on their 2, 4, and 6 cylinder motorcycle engines that are actually inlines ( not the Gold Wings).
On a full out drag engine nobody uses a crossover pipe but it may or may not have some benefit on a street driven inline depending on how the rest of the exhaust system is made up. If you just want to keep the noise down and avoid the sharp split 6 crack then larger pipes and careful choice of mufflers would be the best idea. Muffler location helps too - long tail pipes act as an echo chamber.
Mike G ( 4355 )