Scott,
I too, am the proud owner of the dreaded integral head with the Rochester Varajet, 2SE carb. 1979 Chevy pickup.
I have spoken with Mr. Langdon regarding putting the Holley/Weber on my head. It will not work without an adapter as Mr. Griffin stated. You would have to make or have made, an adapter. The 2 SE is good carb when it is functioning correctly. The secondary has a good size opening. Rebuild kits seems to be plentiful, but if you go that route be sure to provide all the number from the 2SE when ordering. Try to avoid the kit(s) that give you a handful of float bowl gaskets from which to choose. Get the kit specific to that carb. Question, do you have SMOG inspections for registration? If so does it have to be original equipment?
If it does not have to be OE to pass then you have options. The reason I ask, is a "regular" 250 head will bolt right onto the 250 block with the integral head. Same lifters, same pushrods, same headbolts, same thermostat housing, water neck. Then you have many options. You can get 1bbl manifolds, and exhaust manifolds economically and use a 2 bbl adapter. If you choose to hang with the 2SE, your plan to check all the vacuum hoses, and there are a bunch, is a good place to start.
I have put the "regular" 250 head on mine with success so if I can help please ask.
Ken
