What to run will depend on what your plans are for the car. It all has to work together so be realistic about how the car will be used. A big lopey cam with all sorts of compression added sounds wonderful and certainly has bragging rights but if you plan to drive the car you need to skip all the drag strip parts or you won't enjoy it. Putting big parts into and onto a small engine doesn't always work. On the other hand if it will be mostly a legitimate drag car then milder street performance parts won't make you very happy.
Here is what I am running in my 250. A .030" overbore to clean it up, a ton of head work including larger intake valves and semi serious port job. Compression is 9.8 to 1, Offy 4 bbl manifold with a 500cfm Edelbrock carb, Clifford street rod headers into 2 inch dual pipes and mufflers. The engine is fully balanced and clearanced and runs a fully upgraded HEI and an electric fuel pump. Comp 260H cam and spring kit and Crane roller rockers. Behind it is a 15# flywheel and M20 Muncie 4 speed turning back to 3.36 gears in the rear.
This thing runs excellent in traffic and on the highway and can dust off some very surprised small block V8 drivers. The engine has no bad habits and sips down gas at that rate of just under 21 mpg on the highway at 70 mph. Its been in my 37 Chevy for 2 summers now and has recently turned 10K miles.
Get a copy of Leo Santucci's book and read it until the print is worn off the pages. His recommendations are well thought out and will save you time and frustration in the long run.
Take your time and do your homework. You'll be glad when you see the end results.
Mike
