You're not going to fix it until you know what the cam is, both to set the lash and estimate the power range.
Where is the spark set now?
600 is a Holley 4150, yes? What list number? Has primary PV?
"get it to run right", meaning what? Doesn't start? Doesn't idle? Fouls plugs? Overheats?
Compression test shows what?
Leak-down test?