Small block V8 rods are narrower on the big end (crankshaft end)and will not work
Why?
You can install a small block V8 connecting rod in a Chevrolet 250 and the engine will run. The excessive big end rod end play will allow additional oil spray, lowering oil pressure slightly.
The connecting rod big end width is 1.029" for the Chevrolet 250, and 0.941" for the small block V8. That's a difference of 0.088" smaller for the V8 connecting rod. The recommended big end rod end play for the Chevrolet 250 is 0.006" to 0.017". General engine application recommendations go up to about 0.020". So with the SB V8 connecting rod, the connecting rod big end side clearance starts at approximately 0.094" (3/32") and goes up.