I'm going to toss my 2 cents in and say more the merrier.
Having driven a 194 with Powerglide tranny for years, don't underestimate having a gear to down shift to going up hills or passing.
The 250 and 292 was a lot better with the TH350. (3.08 rear)
The 250 with wide ratio Muncie 4 speed was fun too. (3.36 rear)
Faster in 1/4 mile? 60 foot times?
Don't know, just more fun to drive.
Less fun: Interstates! If anyone talks about overdrive trannys listen.
Good luck with your project.