you need to set your timing for the full rpm range.
idle (with no vacum) 8-12
cruise (highway/low load) 40-45
heavy load 32-36
that means you will need to get a dial back timing light.
set initial to: 12
set mech advance to 20 all in by 2000 rpm
set vacum can to 10-12 for highway use.
does any of that make sense?
you can buy a common hei mech advance kit and adjustable vacum can. same as a V8 setup. tom