I highly doubt it. These are completely different engines. As far as I know there's nothing internally or externally interchangeable on these motors -- except that you can modify a 250 HEI/distributor to fit a 261.
1953 2dr 150 with '59 261 1964 Bel Air with stock ~69 230 1961 Biscayne with stuck 235 tore up '53 235