Sure. You can use a factory Duraspark II distributor for a 300 inline six. It drops right in. For additional low cost ideas go to http://www.gofastforless.com and check out the GM HEI module application.
6re6
FORD 300 inline six - THE BEST KEPT SECRET IN DRAG RACING!
Duraspark distributors are great! I have one for my '65 200, with a MOPAR ignition module.........but think I may go to a GM module mounted under the dash, bolted to a heat-sink.