Since it sounds like you want to add positive discplacement air and the 292 has a 4-1/8 stroke I would consider a turbo 400 and a Gear Vender OD unit with the stock style flatbed dually rear if it's in the 4.88 range especially it you plan on towing. 400's are pretty bullet proof especially with a lot of torque.
Turbos also cause a lot of heat under the cab over so you may consider a belt drive blower, ie: Whipple, Procharge, Paxton etc. A Clifford manifolds flows pretty well and have a low profile. A throttle body made of a Holley style carb plate would look great with electronic injectors or use the carb with a pressure top.
Dare to be different you said. Project sounds great. Good Luck
