I bored a mid-'70s 250 block .125 once and ran a stroker assembly in it twice. First time without block fill, second time with block half fill and a rigid hone to true it up. I did install head bolts on spacers around each bore while honing as a poor imitation of torque plate. Unfortunately the block is gone now so I can't sonic check it. Got a couple extra bucks at the scrapyard for that one.

Saw some irregular wear in the bores after running in both cases. Whether it was inaccurate machining, deflection from head bolt tension, or running loads I can't say.

I interpreted it as head bolt tension deflecting the bore. But nothing broke and it ran great. Based on the irregular wear I say .125 was too much. Running stock 250 type rotating assembly and a proper torque plate hone would likely have improved my results.

One example. Your risk tolerance may be different than mine.