The DeSoto would be a lot of work.
DeSoto bore spacing is 4.3125" vs. 292 at 4.400" = .0875" error for each successive cylinder.
The DeSoto heads are all smaller bore than the 292, but will require domes because of the large chambers.
The head bolts are going to be bad because they're also the DeSoto rocker stand bolts, but there's some front-to-back wiggle room.
The easiest fit is to have the DeSoto intake facing the pushrod side of the 292, but because of the difference in cam locations the pushrods might have to pass through the block to reach the rockers.
