Depends on how tall your tires are.
With a 27" tire, it's 3,250 RPM. Perfectly safe, just a bit noisy. Your mileage will stink, though.
IMHO best to get an idea of RPM and speed before you select a cam. The cam choice between a Powerglide with 3.08 gears and a 4-speed with 3.73 is very different.