You need to know what you started with: jets in the primary, and what size are the PVCR holes, and what secondary plate is in there and its hole sizes. And then what was changed during the dyno tune - going up 9 numbers is a LOT, I've gone up to that with open headers but even then it is rare. Sounds too rich now, maybe a crutch for something else not happy?
I ran a R6390 Holley 390cfm on my 250, stock w Clifford 4bbl.
Jets 52 pri and .028 PVCR, 52 sec and .031 PVCR, this is a 4150 carb so it has jets in the secondary not just a plate. It ran so good this way, won many of the shootout runs, so I left it alone.
You'd probably want about 2 numbers richer than mine with your cam and headers but need to know what you have first
