The only 2bbl carbs I like are if theyre progressive. The biggest progressive available afaik is the Pinto Weber carb, about 200cfm at 1.5" Hg which is marginal even for a stock 250cid. So the next common stop is the 390cfm Holley 4bbl. You can always adapt either 4bbl intake down to a 2bbl if you want to try it but I don't see any reason.
Holley also made a progressive 2b carb in a 350 & 500 cfm. I have one of the 350 cfm. carbs. But you will pay dearly for them when you can find them.
Larry/Twisted6 [oooooo] Adding CFM adds boost God doesn't like ugly.