IMO, unless you have a 12 port head, or made dividers to act like one, your best bet is still a carb or TBI so at least all the air is generally supplied with the same fuel mix.
Going port injection will still have lean/rich cylinder imbalances, possibly worse so than a carb/TBI, especially at higher rpm's and loads when the injector is spraying fuel at a closed intake valve, unless the individual cylinder fuel trims are adjusted.
